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Amanullinic acid

Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the mushroom genus Amanita. Amanullinic acid is relatively non-toxic( oral 20 mg/kg in mice).

Toxicology

Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.

References

References

  1. (1978). "Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms". CRC Critical Reviews in Biochemistry.
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peptides amatoxins hepatotoxins
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