Aluminium phosphate

Berlinite

AlPO4 is isoelectronic with Si2O4, silicon dioxide. Berlinite looks like quartz and has a structure that is similar to quartz with silicon replaced by Al and P. The AlO4 and PO4 tetrahedra alternate. Like quartz, AlPO4 exhibits chirality and piezoelectric properties. When heated, crystalline AlPO4 (berlinite) converts to tridymite and cristobalite forms, and this mirrors the behaviour of silicon dioxide.

Uses

Molecular sieves

There are many types of aluminium phosphate molecular sieves, generically known as "ALPOs". The first ones were reported in 1982. They all share the same chemical composition of AlPO4 and have framework structures with microporous cavities. The frameworks are made up of alternating AlO4 and PO4 tetrahedra. The denser cavity-less crystalline berlinite, shares the same alternating AlO4 and PO4 tetrahedra. The aluminophosphate framework structures vary one from another in the orientation of the AlO4 tetrahedra and PO4 tetrahedra to form different-sized cavities, and in this respect they are similar to the aluminosilicate zeolites, which differ in having electrically charged frameworks. A typical preparation of an aluminophosphate involves the hydrothermal reaction of phosphoric acid and aluminium in the form of hydroxide, an aluminium salt such as aluminium nitrate salt or alkoxide under controlled pH in the presence of organic amines. These organic molecules act as templates (now termed structure directing agents, SDAs) to direct the growth of the porous framework.

Other

Along with aluminium hydroxide, aluminium phosphate is one of the most common immunologic adjuvants (efficiency enhancers) in vaccinations. Aluminium adjuvant use is widespread due to its cheap price, long history of use, safety and efficiency with most antigens.

Similar to aluminium hydroxide, AlPO4 is used as an antacid. Up to 20% of aluminium from ingested antacid salts can be absorbed from the gastrointestinal tract – despite some unverified concerns about the neurological effects of aluminium, aluminium phosphate and hydroxide salts are thought to be safe as antacids in normal use, even during pregnancy and breastfeeding.

Additional uses for AlPO4 in combination with or without other compounds are white colorants for pigments, corrosion inhibitors, cements and dental cements. Related compounds have also similar uses. For example, Al(H2PO4)3 is used in dental cements, metal coatings, glaze compositions and refractory binders; and Al(H2PO4)(HPO4) is used cement and refractory binders and adhesives.

Related compounds

AlPO4·2H2O dihydrate is found as the minerals variscite and meta-variscite. Aluminium phosphate dihydrate (variscite and meta-variscite) has a structure that can be regarded as an assembly of tetra- and octahedral units of phosphate anions, aluminium cations and water. Al3+ ions are 6-coordinate and PO43- ions are 4-coordinate.

A synthetic hydrated form, AlPO4·1.5H2O is also known.

References

Citations

References

1. (June 18, 2018). "CRC Handbook of Chemistry and Physics". CRC Press.
2. Pradyot Patnaik. ''Handbook of Inorganic Chemicals''. McGraw-Hill, 2002, {{ISBN. 0-07-049439-8
3. Corbridge, p. 310
4. Tanaka, Y. (2010). "Determination of structural chirality of berlinite and quartz using resonant x-ray diffraction with circularly polarized x-rays". Physical Review B.
5. Crystal growth of an α-quartz like piezoelectric material, berlinite, Motchany A. I., Chvanski P. P., Annales de Chimie Science des Materiaux properties, 2001, 26, 199
6. {{Greenwood&Earnshaw
7. Wilson, ST. (1982). "Aluminophosphate molecular sieves: a new class of microporous crystalline inorganic solids". Journal of the American Chemical Society.
8. (2010-02-17). "Zeolites in Industrial Separation and Catalysis". John Wiley & Sons.
9. Xu, R. (2007). "Chemistry of zeolites and related porous materials: synthesis and structure". John Wiley & Sons.
10. (2015). "Drugs during pregnancy and lactation: treatment options and risk assessment". Elsevier Science.
11. (2018). "Antacids". StatPearls Publishing.
12. Corbridge, p. 1025
13. Roncal-Herrero, T. (2009-12-02). "Precipitation of Iron and Aluminum Phosphates Directly from Aqueous Solution as a Function of Temperature from 50 to 200 °C". Crystal Growth & Design.
14. Corbridge, p. 207-208
15. (2005). "Synthesis of Hydrated Aluminium Phosphate, AlPO₄·1.5H₂O (AlPO₄−H₃), by Controlled Reactive Crystallization in Sulfate Media". Industrial & Engineering Chemistry Research.