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All-trans-octaprenyl-diphosphate synthase

Class of enzymes

Field	Value
Name	All-trans-octaprenyl-diphosphate synthase
EC_number	2.5.1.90
image	PDB 1v4e EBI.jpg

All-trans-octaprenyl-diphosphate synthase (, octaprenyl-diphosphate synthase, octaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-heptaprenyltranstransferase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units). This enzyme catalyses the following chemical reaction

: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate \rightleftharpoons 5 diphosphate + all-trans-octaprenyl diphosphate

This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate.

References

(May 1986). "Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis". Journal of Biochemistry.
(July 1994). "The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase". Biochemical and Biophysical Research Communications.

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ec-2.5.1

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