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Adenoma sebaceum

Field	Value
synonym	Facial angiofibroma
image	File:Wax moulage, side view of a child’s face showing ‘adenoma sebaceum’ (a genetic skin disorder), early twentieth century (23966574919).jpg
caption	Wax moulage, side view of a child's face showing 'adenoma sebaceum' (a genetic skin disorder), early twentieth century
specialty	Dermatology

Adenoma sebaceum, also known as facial angiofibroma is a misnamed cutaneous disorder consisting of angiofibromas that begin in childhood (generally present between 2–5 years of age) and appear clinically as red papules on the face especially on the nasolabial folds, cheek and chin, often misidentified as acne not responding to treatment. Adenoma sebaceum may at times be associated with tuberous sclerosis. Gradually the papules become more prominent with time and persist throughout life. Cosmetic removal by argon or pulse dye laser or scalpel is indicated.

Signs and symptoms

Adenoma sebaceum are several tiny, pinkish, erythematous hamartomas that cover the nose and cheeks in a distinctive butterfly pattern during early childhood or infancy. They typically occur in the nasolabial folds and are symmetrical.

Diagnosis

Adenoma sebaceum presence represents one of the major diagnostic criteria to confirm the diagnosis of tuberous sclerosis. When adenoma sebaceum presents with seizures and mental retardation (Vogt's triad), it indicates that cranial imaging is necessary, other differential diagnoses for this disorder include acne vulgaris, rhinophyma, and sebaceous hyperplasia.

Treatment

Adenoma sebaceum can be eliminated with dermabrasion or a laser.

References

Marks, James G; Miller, Jeffery (2006). ''Lookingbill and Marks' Principles of Dermatology'' (4th ed.). Elsevier Inc. {{ISBN. 1-4160-3185-5.
(2006). "Andrews' Diseases of the Skin: Clinical Dermatology". Saunders Elsevier.
"DermIS — Adenoma Sebaceum (information on the diagnosis)".
(2022-09-14). "Characterization and management of facial angiofibroma related to tuberous sclerosis complex in the United States: retrospective analysis of the natural history database". Springer Science and Business Media LLC.
Osborne, J P. (1988-12-01). "Diagnosis of tuberous sclerosis.". BMJ.
(2009-01-01). "Papulonodular lesions in a man with seizures and mental retardation. Adenoma sebaceum". American Family Physician.
(1988-09-01). "DUP 785 (NSC 368390): schedule-dependency of growth-inhibitory and antipyrimidine effects". Biochemical Pharmacology.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

dermal-and-subcutaneous-growths

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