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Acquired hemolytic anemia

Field	Value
name	Acquired hemolytic anemia
field	Hematology

Acquired hemolytic anemia can be divided into immune and non-immune mediated forms of hemolytic anemia.

Classification

Immune

Autoimmune hemolytic anemia
- Warm antibody autoimmune hemolytic anemia
  - Idiopathic
  - Linked with primary immunodeficiency/immunodysregulation syndrome.
  - Lymphoma or chronic lymphocytic leukemia associated.
  - Secondary to other malignancies.
  - Associated with SLE or other collagen-vascular disorders.
  - Secondary to viral infection.
- Cold antibody autoimmune hemolytic anemia
- Paroxysmal cold hemoglobinuria
- Drug-induced autoimmune hemolytic anemia
Alloimmune hemolytic anemia
- Hemolytic disease of the newborn (HDN)
  - Rh disease (Rh D)
  - ABO hemolytic disease of the newborn
  - Anti-Kell hemolytic disease of the newborn
  - Rhesus c hemolytic disease of the newborn
  - Rhesus E hemolytic disease of the newborn
  - Other blood group incompatibility (RhC, Rhe, Kidd, Duffy, MN, P and others)
- Alloimmune hemolytic blood transfusion reactions (i.e., from a non-compatible blood type)

Non-immune

Traumatic hemolytic anemia
- Impact
- Macrovascular defects-prostheses
- Microvascular causes
  - Disseminated intravascular hemolysis
  - Thrombotic thrombocytopenic purpura
  - Typical and atypical hemolytic uremic syndrome
  - Other microvascular abnormalities
- Hypersplenism
- Hemolytic anemia due to toxic effects on the membrane
  - Spur cell anemia
  - External toxins
    - Animal or spider bites
    - Metals
    - Organic compounds
  - Infectious agents
Paroxysmal nocturnal hemoglobinuria (PNH)

History

The term 'acquired hemolytic anemia' originally appeared in the early 1900s.

References

(2011). "Blood and Bone Marrow Pathology". Elsevier.
Kalfa, Theodosia A.. (2019). "Concise Guide to Hematology". Springer International Publishing.
(2000). "Autoimmune hemolytic anemia: A history*". Elsevier BV.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

acquired-hemolytic-anemia

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