Surf Wiki
Save to docs
general/cyclitols

From Surf Wiki (app.surf) — the open knowledge base

5-Deoxyinositol

5-Deoxyinositol (quercitol) is a cyclitol. It can be found in wines aged in oak wood barrels. It can also be found in Quercus sp. (oaks) and in Gymnema sylvestre. It is different from , a synonym of quercetin.

Biosynthesis

The proposed biosynthesis of 5-deoxyinositol begins with the conversion of D-glucose to myo-inositol. In this pathway, D-glucose is phosphorylated to form D-glucose-6-phosphate. The NAD+ dependent enzyme inositol 1-phosphate synthase (I1PS) then catalyzes the subsequent oxidation, enolization, aldol cyclization, and reduction of D-glucose 6-phosphate to form myo-inositol 1-phosphate. Hydrolysis of the phosphate group on this molecule gives myo-inositol. Myo-inositol can then be converted into 5-deoxyinositol in three steps, beginning with the oxidation of myo-inositol by inositol dehydrogenase (ID) to form scyllo-inosose. This intermediate is then dehydrated to form a diketone. The reduction of this diketone gives 5-deoxyinositol. This final reduction is thought to be catalyzed by one or more unidentified reductases or dehydrogenases.

:[[File:5-deoxyinositol biosynthesis.svg|thumb|left|600px|Biosynthesis of 5-deoxyinositol]]

References

References

  1. ''[[Merck Index]]'', 12th Edition, '''8218'''
  2. Davinia Carlavilla. (2006). "Occurrence and Significance of Quercitol and Other Inositols in Wines during Oak Wood Aging". Am. J. Enol. Vitic..
  3. Sonia Rodríguez-Sánchez. (2010). "Analysis of cyclitols in different Quercus species by gas chromatography–mass spectrometry". Journal of the Science of Food and Agriculture.
  4. (1997-09-04). "1L-myo-inositol-1-phosphate synthase". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism.
  5. (2008-04-18). "myo-Inositol catabolism in Bacillus subtilis". The Journal of Biological Chemistry.
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

cyclitols
Want to explore this topic further?

Ask Mako anything about 5-Deoxyinositol — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report