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4-Hydroxybenzoate geranyltransferase

Class of enzymes

Class of enzymes

FieldValue
Name4-hydroxybenzoate geranyltransferase
EC_number2.5.1.93

4-hydroxybenzoate geranyltransferase (, PGT1, PGT2, 4HB geranyltransferase, 4HB:geranyltransferase, p-hydroxybenzoate geranyltransferase, PHB geranyltransferase, geranyl diphosphate:4-hydroxybenzoate geranyltransferase) is an enzyme with systematic name geranyl-diphosphate:4-hydroxybenzoate 3-geranyltransferase. This enzyme catalyses the following chemical reaction

: geranyl diphosphate + 4-hydroxybenzoate \rightleftharpoons 3-geranyl-4-hydroxybenzoate + diphosphate

The enzyme is involved in shikonin biosynthesis. It has a strict substrate specificity for geranyl diphosphate and an absolute requirement for Mg2+.

References

References

  1. (June 2009). "Functional characterization of LePGT1, a membrane-bound prenyltransferase involved in the geranylation of p-hydroxybenzoic acid". The Biochemical Journal.
  2. (July 1998). "4-Hydroxybenzoate 3-geranyltransferase from Lithospermum erythrorhizon: purification of a plant membrane-bound prenyltransferase". Planta.
  3. (February 2002). "Geranyl diphosphate:4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon. Cloning and characterization of a ket enzyme in shikonin biosynthesis". The Journal of Biological Chemistry.
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ec-2.5.1
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