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4-(Gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase

Class of enzymes

Field	Value
Name	4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase
EC_number	1.14.14.13

4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase (, btrO (gene)) is an enzyme with systematic name 4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein),FMN:oxygen oxidoreductase (2-hydroxylating). This enzyme catalyses the following chemical reaction

: 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] + FMNH2 + O2 \rightleftharpoons 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] + FMN + H2O

4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.

References

(June 2005). "Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway". Chemistry & Biology.

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ec-1.14.14

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