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3-hydroxyindolin-2-one monooxygenase

Class of enzymes


Class of enzymes

FieldValue
Name3-hydroxyindolin-2-one monooxygenase
EC_number1.14.13.139

3-hydroxyindolin-2-one monooxygenase (, BX4 (gene), CYP71C1 (gene)) is an enzyme with systematic name 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming). This enzyme catalyses the following chemical reaction

: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 \rightleftharpoons 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O

3-hydroxyindolin-2-one monooxygenase is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.

References

References

  1. (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry.
  2. (August 1997). "Analysis of a chemical plant defense mechanism in grasses". Science.
  3. (June 2001). "Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays". Phytochemistry.
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