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3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

Class of enzymes

Class of enzymes

FieldValue
Name3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase
EC_number1.14.14.12

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase (, HsaA) is an enzyme with systematic name **. This enzyme catalyses the following chemical reaction:

: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 \rightleftharpoons 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O

This bacterial enzyme participates in the degradation of several steroids, including cholesterol and testosterone.

References

References

  1. (July 2010). "A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism". The Journal of Biological Chemistry.
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ec-1.14.14
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