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3-(3-hydroxyphenyl)propanoate hydroxylase

Class of enzymes

Class of enzymes

FieldValue
Name3-(3-hydroxyphenyl)propanoate hydroxylase
EC_number1.14.13.127

3-(3-hydroxyphenyl)propanoate hydroxylase (, mhpA (gene)) is an enzyme with systematic name 3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating). This enzyme catalyses the following chemical reaction

: (1) 3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2 \rightleftharpoons 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+ : (2) (2E)-3-(3-hydroxyphenyl)prop-2-enoate + NADH + H+ + O2 \rightleftharpoons (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD+

3-(3-hydroxyphenyl)propanoate hydroxylase is a flavoprotein (FAD).

References

References

  1. (July 1983). "Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli". Journal of Bacteriology.
  2. (October 1986). "Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation". Journal of Bacteriology.
  3. (April 1997). "Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12". Journal of Bacteriology.
  4. (June 1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12". Journal of Bacteriology.
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