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23S rRNA (guanine1835-N2)-methyltransferase

Class of enzymes

Class of enzymes

FieldValue
Name23S rRNA (guanine1835-N2)-methyltransferase
EC_number2.1.1.174

23S rRNA (guanine1835-N2)-methyltransferase (, ygjO (gene), rlmG (gene), ribosomal RNA large subunit methyltransferase G) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + guanine1835 in 23S rRNA \rightleftharpoons S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA

The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.

References

References

  1. (November 2006). "Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA". Journal of Molecular Biology.
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ec-2.1.1
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