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2-Hexanone

Chemical compound (C6H12O)


Summary

Chemical compound (C6H12O)

| NFPA-H = 2 | NFPA-F = 3 | NFPA-R = 0 2430 mg/kg (oral, mouse) 4860 mg/kg (dermal, rabbit) 2590 mg/kg (oral, guinea pig)

2-Hexanone (methyl butyl ketone, MBK) is a ketone used as a general solvent and in paints. It dissolves cellulose nitrate, vinyl polymers and copolymers, and natural and synthetic resins. It is recommended as a solvent because it is photochemically inactive; however it has a very low safe threshold limit value. 2-Hexanone is absorbed through the lungs, orally and dermally and its metabolite, 2,5-hexanedione, is neurotoxic. Animal tests have shown that the neurotoxic effect of 2-hexanone may be potentiated by simultaneous administration of 2-butanone (methyl ethyl ketone, MEK).

References

References

  1. ''[[Merck Index]]'', 11th Edition, '''5955'''.
  2. CRC Handbook of Chemistry and Physics, 75th ed. (1995)
  3. {{PGCH. 0325
  4. {{IDLH. 591786. 2-Hexanone
  5. Dieter Stoye. (2007). "[[Ullmann's Encyclopedia of Industrial Chemistry]]". Wiley.
  6. Jerrold B. Leikin. (2008). "Poisoning and Toxicology Handbook". Informa.
  7. Wilhelm Neier. (2007). "Ullmann's Encyclopedia of Industrial Chemistry". Wiley.
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