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1,3-Difluoro-2-propanol


1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor which was widely used in the former USSR and still approved in China.

References

References

  1. [http://www.sigmaaldrich.com/catalog/product/aldrich/176923?lang=en&region=US Sigma Aldrich]
  2. (1986). "[Gliftor poisoning]". Sudebno-Meditsinskaia Ekspertiza.
  3. (1998). "The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote". Journal of Biochemical and Molecular Toxicology.
  4. (2001). "The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (−)-erythro-fluorocitrate". Journal of Biochemical and Molecular Toxicology.
  5. "Gliftor".
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