From Surf Wiki (app.surf) — the open knowledge base

Salivary gland–like carcinoma of the lung

Field	Value
specialty	oncology

Salivary gland–like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell division (mitosis) of mutated cancer stem cells in lung tissue. They take their name partly from the appearance of their abnormal cells, whose structure and features closely resemble those of cancers that form in the major salivary glands (parotid glands, submandibular glands and sublingual glands) of the head and neck. Carcinoma is a term for malignant neoplasms derived from cells of epithelial lineage, and/or that exhibit cytological or tissue architectural features characteristically found in epithelial cells.

Types

This class of primary lung cancers contains several histological variants, including mucoepidermoid carcinoma of the lung, adenoid cystic carcinoma of the lung, epithelial-myoepithelial carcinoma of the lung, and other (even more rare) variants.

Diagnosis

Classification

Lung cancer is a large and exceptionally heterogeneous family of malignancies. Over 50 different histological variants are explicitly recognized within the 2004 revision of the World Health Organization (WHO) typing system ("WHO-2004"), currently the most widely used lung cancer classification scheme. Many of these entities are rare, recently described, and poorly understood. However, since different forms of malignant tumors generally exhibit diverse genetic, biological, and clinical properties — including response to treatment — accurate classification of lung cancer cases are critical to assuring that patients with lung cancer receive optimum management.

Under WHO-2004, lung carcinomas are divided into 8 major taxa:

Squamous cell carcinoma
Small cell carcinoma
Adenocarcinoma
Large cell carcinoma
Adenosquamous carcinoma
Sarcomatoid carcinoma
Carcinoid tumor
Salivary gland-like carcinoma

Treatment

Treatment options may include surgery, radiation, and chemotherapy. Icotinib has been temporarily effective at treating salivary gland-like carcinoma of the lung but loses efficiency after three months.

References

(2004). "Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart". IARC Press.
(January 1995). "Lung cancer". Cancer.
(June 1985). "Lung cancer heterogeneity: a blinded and randomized study of 100 consecutive cases". Hum. Pathol..
(December 2001). "The new World Health Organization classification of lung tumours". Eur. Respir. J..
Rossi G, Marchioni A, Sartori1 G, Longo L, Piccinini S, Cavazza A. (2007). "Histotype in non-small cell lung cancer therapy and staging: The emerging role of an old and underrated factor". Curr Respir Med Rev.
Vincent MD. (August 2009). "Optimizing the management of advanced non-small-cell lung cancer: a personal view". Curr Oncol.
(2021-08-08). "Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report". Wiley.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

lung-cancer rare-cancers

Want to explore this topic further?

Ask Mako anything about Salivary gland–like carcinoma of the lung — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report