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O-phospho-L-seryl-tRNA:Cys-tRNA synthase

FieldValue
NameO-phospho-L-seryl-tRNA:Cys-tRNA synthase
EC_number2.5.1.73
CAS_number1239229-21-0

O-phospho-L-seryl-tRNA:Cys-tRNA synthase (, SepCysS, Sep-tRNA:Cys-tRNA synthase) is an enzyme with systematic name O-phospho-L-seryl-tRNACys:hydrogen sulfide 2-aminopropanoate transferase. This enzyme catalyses the following chemical reaction

: O-phospho-L-seryl-tRNACys + sulfide \rightleftharpoons L-cysteinyl-tRNACys + phosphate

References

References

  1. (June 2007). "Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus". Journal of Molecular Biology.
  2. (August 2008). "Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei". The Journal of Biological Chemistry.
  3. (December 2006). "RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea". Proceedings of the National Academy of Sciences of the United States of America.
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ec-2.5.1
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