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Morgagni–Stewart–Morel syndrome


FieldValue
synonymsHyperostosis frontalis interna,' Metabolic craniopathy
imageX-linked recessive.svg
image_size160px
captionMorgagni–Stewart–Morel syndrome is inherited in an X-linked recessive manner (or autosomal dominant).
fieldEndocrinology

Morgagni–Stewart–Morel syndrome is a condition with a wide range of associated endocrine problems including: diabetes mellitus, diabetes insipidus, and hyperparathyroidism. Other signs and symptoms include headaches, vertigo, hirsutism, menstrual disorder, galactorrhoea, obesity, depression, and seizures. It is named after the Italian anatomist and pathologist Giovanni Battista Morgagni, the British neurologist Roy Mackenzie Stewart, and the Swiss psychiatrist Ferdinand Morel.

Cause

Diagnosis

The diagnosis of Morgagni–Stewart–Morel is based upon a radiological finding of hyperostosis frontalis interna. Diagnosis considers a combination of clinical features including obesity, virilism, and mental disturbances.

Treatment

Treatment is based upon the symptoms, and generally includes medication, diet and lifestyle modification for weight control. Seizures and headaches associated with hyperostosis frontalis interna (HFI) are treated with standard medications.

References

References

  1. "Morgagni Stewart Morel syndrome".
  2. (March 2005). "Morgagni Stewart Morel syndrome—additional features". Neurol India.
  3. (2004). "Hyperostosis frontalis interna: case report and review of literature". Ann. Clin. Lab. Sci..
  4. "Obesity: MedlinePlus Medical Encyclopedia".
  5. "Morgagni-Stewart-Morel syndrome {{!}} Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".
  6. "Morgagni-Stewart-Morel syndrome {{!}} Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".
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