Lopez vs Lopez

Lopez vs Lopez is an American sitcom created by George Lopez, Mayan Lopez and Debby Wolfe that premiered on NBC on November 4, 2022. Wolfe also serves as showrunner with Bruce Helford and is executive producer. It stars Lopez and his daughter Mayan as fictionalized versions of themselves along with Matt Shively, Brice Gonzalez, Al Madrigal, and Selenis Leyva in supporting roles. This series marked Lopez's second return to television series since Lopez ended in 2017. In May 2023, the series was renewed for a second season which premiered on April 2, 2024. In May 2024, the series was renewed for a third season which premiered on October 18, 2024. In May 2025, the series was canceled after three seasons.

George, the owner of a moving company that went bankrupt is forced to move into his daughter Mayan’s house. The problem is that Mayan and George have just started speaking after being estranged for most of her teenage years. Now they seek to heal their relationship and learn more about each other. With this, Mayan, along with her boyfriend, Quinten, and their son, Chance, are trying to adjust to their new living arrangements with George. In addition, they are also having to adapt to Mayan's mom and George's ex-wife, Rosie, dropping by unannounced, usually to either see Mayan, or to throw shade at George.

• George Lopez as Himself, Mayan's father

• Mayan Lopez as Herself, George's daughter

• Matt Shively as Quinten Mark Van Bryan, Mayan's fiance

• Brice Gonzalez as Chance Lopez-Van Bryan, Mayan & Quinten's son and George's grandson

• Selenis Leyva as Rosie Flores Lopez, George's ex-wife and Mayan's mother

• Al Madrigal as Oscar Rivera, an employee and friend of George's who is frequently stoned

• Noel the Rescue Dog as Churro, the chihuahua family Dog

• Laci Mosley as Brookie, Mayan's co-worker and friend

• Aparna Nancherla as Dr. Pocha, a veterinarian and Mayan's boss

• Caroline Rhea as Jana, a rich pushy lady at Mayan's vet

• Moises Chavez as Raul, one of George's employees and friends

• Liz Torres as Daisy, Rosie's sister

• Rita Moreno as Dolores Lopez, George's grandmother

• Cheech Marin as Carlos, Rosie's Curandero

• Stephen Tobolowsky as Sam Van Bryan, Quinten's father

• Momo Rodriguez as Momo, one of George's employees and friends

• Jaime Camil as Josué Consuelos, Rosie's boyfriend

• Terri Hoyos as Elsa Lopez, George's mother

• Jerry Garcia as Mando, one of George's employees who has become a friend

• Adam Kulbersh as Jerry, a Homeowner association member who collects action figures

• Maria Canals-Barrera as Lily, Rosie's sister

• Ana Rey as Flor, Rosie's sister

• Nathan Miranda as Robbie

• Constance Marie as Connie

• Valente Rodriguez as Val

• Luis Armand Garcia as Louie

• Belita Moreno as Bella

• Michelle Ortiz as Mrs. Garcia, Chance's substitute teacher

• Neil Flynn as Steve, June's father and George's enemy

• Eden Sher as June, Steve's daughter and Mayan's friend

• Kensie Mills as Paloma, Steve's granddaughter and June's daughter

• Sophia Magaña as Young Mayan

• Harvey Guillen as Miguel, Mayan's cousin

• Jessica Marie Garcia as Yesika, Mayan's cousin

• Chelsea Rendon as Luna, Mayan's cousin

• Jacob Vargas as Javier, Rosie's client

• Gregg Sulkin as Dr. Bell

• Justina Machado as Beatrice 'Bunny' Perez, Rosie's friend

• Lidia Porto as Gina

• Erik Griffin as Don Patino, Mayan's ex-godfather

• Marilyn Milian as Judge Justicia, a latina TV judge

• Jesus Zapien as Mr. Reyes

• Julie Wittner as Jenny, a client

• Danny Trejo as Danny Martinez, George's rival

• Melissa Fumero as Natalia, a latina single mom

• Snoop Dogg as Calvin, George's new sponsor

• Gabriel "Fluffy" Iglesias as Iggy, George's sponsor

• Vanessa Gonzalez as Gladys, a waitress

• Diana-Maria Riva as Olga, a swap meet vendor

• Alexandra Madison as Kylie

• Jon Bouffard as Jax

• Tommy Chong as Bryan, Oscar's new friend

• Marshawn Lynch as Marshawn, a sideline reporter

• Jim Plunkett as Himself

• Pedro Lopez as Walter

• Scheana Shay as Erica, Justin's husband

• Brock Davies as Justin, Erica's wife

• Lisa Rinna as Lisa Perry, George's client

• Jackie Guerrido as Valencia Santa Domingo

• Michael Irby as Father Ramirez, a pastor

• Tisha Campbell as Dr. Glenda Brenda, Mayan's therapist

• Anthony Anderson as Todd Cheeks

• Mini Kiss as Themselves

• Michael Blaiklock as Nick

• Meredith Paul as Becky

• Al Coronel as Tío Pablo

• Eileen Galindo as Tía Angela

• Vicki Lawrence as Ruthie Van Bryan, Quinten's mother

• Jeff Ross as Jeff, a friend of George's

• Adrian Gonzalez as Rico

• Annie Gonzalez as Annie Dominguez, Mayan's best friend from high school

• Adam Irigoyen as Orlando, Rosie's nephew

• Eli Greenberg as Iker

• Hannah Zamora as Yesi

• Brian Posehn as Nicolas, a Mall Santa who reminds George

• George Paez as Joseph

• Tina D'Marco as Irma

• Francia Raisa as Carina, an entitled social media influencer

• Rizwan Manji as Crispin, an arrogant hardware store employee

• Alexandra Billings as Paula, an exhausted legal mediator who reluctantly presides over Rosie's dispute with her ex-fiance, Josué

• Chris Estrada as Roberto, Quinten's boss

• Santino Jimnez as Gabriel

• Olivia London Leyva as Sofia

• Mario Lopez as Manny, George's cousin

The series is created by George Lopez, his daughter Mayan Lopez, and Debby Wolfe, the latter of whom serves as showrunner. The other executive producers are Bruce Helford, George Lopez, Michael Rotenberg, and Katie Newman. Mayan Lopez is also a producer in the writers' room. On June 14, 2021, the series received a put pilot commitment by NBC. On October 22, 2021, the series was given a pilot order. On April 20, 2022, it was announced that Kelly Park would direct the pilot. On May 11, 2022, the series had been given a series order. On December 2, 2022, NBC ordered nine additional episodes, bringing up the season to a total of 22 episodes. On May 12, 2023, NBC renewed the series for a second season. On November 17, 2023, NBC reduced the number of episodes for the second season from 13 to 10. On May 7, 2024, NBC renewed the series for a third season. On November 15, 2024, the series was given additional script orders, making the season total of 13 episodes. On May 9, 2025, NBC canceled the series after three seasons.

On April 6, 2022, Selenis Leyva, Al Madrigal, Brice Gonzalez and Matt Shively were cast in main roles for the pilot. Two weeks later, Laci Mosley and Aparna Nancherla were cast in recurring roles for the pilot.

Lopez vs Lopez was filmed at Universal Studios Hollywood in Universal City, California, but it is set in Los Angeles, California.

Lopez vs Lopez premiered on November 4, 2022, on NBC. The first season is available to stream on Netflix. The second season premiered on April 2, 2024. The third season premiered on October 18, 2024.

In Canada, the show aired an hour earlier than the American airtime on Citytv.

George Lopez was nominated at the 2025 Kids' Choice Awards for Favorite Male TV Star (Family).

• Official website
• Lopez vs Lopez at IMDb