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Acetyl-S-ACP:malonate ACP transferase

Class of enzymes


Summary

Class of enzymes

FieldValue
NameAcetyl-S-ACP:malonate ACP transferase
EC_number2.3.1.187

Acetyl-S-ACP:malonate ACP transferase (, acetyl-S-ACP:malonate ACP-SH transferase, acetyl-S-acyl-carrier protein:malonate acyl-carrier-protein-transferase, MdcA, MadA, ACP transferase, malonate/acetyl-CoA transferase, malonate:ACP transferase, acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase) is an enzyme with systematic name acetyl-(acyl-carrier-protein):malonate S-(acyl-carrier-protein)transferase. This enzyme catalyses the following chemical reaction

: acetyl-[acyl-carrier protein] + malonate \rightleftharpoons malonyl-[acyl-carrier protein] + acetate

This is the first step in the catalysis of malonate decarboxylation.

References

References

  1. (1994). "Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase". Archives of Microbiology.
  2. (June 1997). "Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli". European Journal of Biochemistry.
  3. (December 1999). "Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus". European Journal of Biochemistry.
  4. (January 2003). "Functions of malonate decarboxylase subunits from Pseudomonas putida". Bioscience, Biotechnology, and Biochemistry.
  5. (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology.
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