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5-MeO-NBpBrT
| Column 1 |
|---|
| 5-Methoxy-N-(4-bromobenzyl)tryptamine |
| .mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}None |
| IUPAC name |
| N-(4-Bromobenzyl)-2-(5-methoxy-1H-indol-3-yl)ethanamine |
| 155639-13-7 N |
| 5124753 |
| 4299315 Y |
| UG43REN7BR |
| ChEMBL57427 Y |
| DTXSID901029953 |
| C18H19BrN2O |
| 359.267 g·mol−1 |
| Interactive image |
| SMILES |
| BrC1=CC=C(CNCCC2=CNC3=CC=C(OC)C=C23)C=C1 |
| InChI |
| InChI=1S/C18H19BrN2O/c1-22-16-6-7-18-17(10-16)14(12-21-18)8-9-20-11-13-2-4-15(19)5-3-13/h2-7,10,12,20-21H,8-9,11H2,1H3 YKey:XHLOUFPZLUULGI-UHFFFAOYSA-N Y |
| .mw-parser-output .nobold{font-weight:normal} NY (what is this?) (verify) |
5-MeO-NBpBrT, also known as 5-methoxy-N-(4-bromobenzyl)tryptamine, is an N-substituted member of the 5-methoxytryptamine family of compounds. Like other such compounds, it acts as an antagonist for the serotonin 5-HT2A receptor, with a claimed 100-fold selectivity over the closely related serotonin 5-HT2C receptor. While N-benzyl substitution of psychedelic phenethylamines often results in potent serotonin 5-HT2A agonists, it had been thought that N-benzyltryptamines show much lower efficacy and are either very weak partial agonists or antagonists at the serotonin 5-HT2A receptor, though more recent research has shown stronger agonist activity for 3-substituted benzyl derivatives. Extending the benzyl group to a substituted phenethyl can also recover agonist activity in certain cases.
- Substituted tryptamine
- 25B-NBOMe
- 25I-NBF
- 5-MeO-T-NBOMe
- 5-MeO-T-NB3OMe
- RH-34
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