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5-HO-DiPT

Column 1


5-OH-DiPT; 5-Hydroxy-N,N-diisopropyltryptamine
IUPAC name
3-(2-(diisopropylamino)ethyl)-1H-indol-5-ol
.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}36288-76-3 N
71360804
29358411
G7I3OBF3XM
DTXSID80784573
C16H24N2O
260.381 g·mol−1
Interactive image
SMILES
CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C
InChI
InChI=1S/C16H24N2O/c1-11(2)18(12(3)4)8-7-13-10-17-16-6-5-14(19)9-15(13)16/h5-6,9-12,17,19H,7-8H2,1-4H3Key:HWOLNTJLIUHEOG-UHFFFAOYSA-N

5-HO-DiPT, also known as 5-hydroxy-N,N-di-iso-propyltryptamine, is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.

Analogues of 5-HO-DiPT include diisopropyltryptamine (DiPT), 4-HO-DiPT (iprocin), 4-AcO-DiPT (ipracetin), 5-MeO-DiPT, bufotenin (5-HO-DMT), 5-AcO-DMT, 5-HO-MET, 5-HO-DET, 5-HO-DPT, and α-methylserotonin (5-HO-AMT), among others.

Substituted tryptamine
5-HO-DiPT - Isomer Design

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