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5-Fluoro-EPT


Column 1
IUPAC name
N-ethyl-N-[2-(5-fluoro-1H-indol-3-yl)ethyl]propan-1-amine
.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}2698331-33-6 Y
156836218
129221323
ChEMBL5028990
C15H21FN2
248.345 g·mol−1
Interactive image
SMILES
CCCN(CC)CCC1=CNC2=C1C=C(C=C2)F
InChI
InChI=1S/C15H21FN2/c1-3-8-18(4-2)9-7-12-11-17-15-6-5-13(16)10-14(12)15/h5-6,10-11,17H,3-4,7-9H2,1-2H3Key:QONMHCQBCANXJS-UHFFFAOYSA-N

5-Fluoro-EPT (5F-EPT, 5-fluoro-N-ethyl-N-propyltryptamine) is a psychedelic tryptamine derivative related to drugs such as EPT and 5-MeO-EPT. It acts as a potent full agonist at the 5-HT2A receptor with an EC50 of 5.54 nM and an efficacy of 104% (compared to serotonin). It produces a head-twitch response in animal studies, and is claimed to have antidepressant activity.

  • Substituted tryptamine
  • 5-Fluoro-AMT
  • 5-Fluoro-AET
  • 5-Fluoro-DMT
  • 5-Fluoro-DET
  • 5-Fluoro-MET
  • 5-Fluoro-T
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