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2C-CPe


Column 1
2C-CPE; 4-Cyclopentyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-cyclopentylphenethylamine
IUPAC name
2-(4-cyclopentyl-2,5-dimethoxyphenyl)ethanamine
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C15H23NO2
249.354 g·mol−1
Interactive image
SMILES
COC1=CC(=C(C=C1CCN)OC)C2CCCC2
InChI
InChI=1S/C15H23NO2/c1-17-14-10-13(11-5-3-4-6-11)15(18-2)9-12(14)7-8-16/h9-11H,3-8,16H2,1-2H3Key:GIYHLPFOZWFVHO-UHFFFAOYSA-N

2C-CPe, also known as 4-cyclopentyl-2,5-dimethoxyphenethylamine, is a designer drug from the substituted phenethylamine family, which was first synthesised by Josh Hartsel and colleagues in 2024. It is a moderately potent agonist at the serotonin receptor 5-HT2A in vitro, with a binding affinity (Ki) of 134 nM, slightly weaker than the related cyclopropyl compound 2C-CP. It is not known to have been tested in humans or animals. It is a controlled substance in Canada under phenethylamine blanket-ban language.

  • 2C (psychedelics)

  • 2C-P

  • 2C-Bu

  • 2C-iBu

  • 2C-CPe - Isomer Design

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