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2-Hydroxyethyl terephthalic acid


Column 1Column 2
Preferred IUPAC name
4-[(2-Hydroxyethoxy)carbonyl]benzoic acid
Other names
1,4-Benzenedicarboxylic acid, 1-(2-hydroxyethyl) ester
CAS Number.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}1137-99-1 Y
3D model (JSmol)Interactive image
ChEBICHEBI:131735
ChemSpider151881
EC Number875-651-4
KEGGC21450
PubChem CID174073
UNII8DN7KSY2WN Y
CompTox Dashboard (EPA)DTXSID60622186
InChI
InChI=1S/C10H10O5/c11-5-6-15-10(14)8-3-1-7(2-4-8)9(12)13/h1-4,11H,5-6H2,(H,12,13)Key: BCBHDSLDGBIFIX-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1C(=O)O)C(=O)OCCO
Chemical formulaC10H10O5
Molar mass210.185 g·mol−1
AppearanceWhite solid
Melting point183–186 °C (361–367 °F; 456–459 K)
GHS labelling:[1]
Pictograms
Signal wordWarning
Hazard statementsH302, H315, H319, H335
Precautionary statementsP261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references | |

2-Hydroxyethyl terephthalic acid is an organic compound with the formula HOC2H4O2CC6H4CO2H. It is the monoester of terephthalic acid and ethylene glycol. The compound is a precursor to poly(ethylene terephthalate) (PET), a polymer that is produced on a large scale industrially. 2-Hydroxyethyl terephthalic acid is a colorless solid that is soluble in water and polar organic solvents. Near neutral pH, 2-hydroxyethyl terephthalic acid converts to 2-hydroxyethyl terephthalate, HOC2H4O2CC6H4CO2−.

2-Hydroxyethyl terephthalic acid is an intermediate in both the formation and hydrolysis of PET. It is produced on a massive scale as the first intermediate in certain routes to PET. Specifically, it is produced in the course of the thermal condensation of terephthalic acid and ethylene glycol:

HOC2H4OH + HO2CC6H4CO2H → HOC2H4O2CC6H4CO2H + H2O

Further dehydration of 2-hydroxyethyl terephthalic acid gives PET.

It is also produced by the partial hydrolysis of PET, as catalyzed by the enzyme PETase. It is substrate for the enzyme MHETase.

H[O2CC6H4CO2C2H4]nOH + (n−1) H2O → n HO2CC6H4CO2C2H4OH

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