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10,11-Seco-LSD

Column 1

"[0124]"; 9,10-Didehydro-N,N-diethyl-6-methyl-10,11-secoergoline-8β-carboxamide
Partial ergoline
.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}None
2640392-96-5
Interactive image
SMILES
O=C([C@@]1C=CC@@(CC2=CN([H])C3=CC=CC=C23)N(C)C1)N(CC)CC
InChI
InChI=1S/C20H26N3O/c1-4-23(5-2)20(24)15-10-11-17(22(3)14-15)12-16-13-21-19-9-7-6-8-18(16)19/h6-11,13,17,21H,4-5,12,14H2,1-3H3/t17-/m0/s1Key:CGFPZODXTFFRAH-KRWDZBQOSA-N

10,11-Seco-LSD is a partial lysergamide and cyclized tryptamine related to lysergic acid diethylamide (LSD). It is the seco analogue of LSD in which the bond between the 10 and 11 positions of the ergoline ring system has been broken. 10,11-Seco-LSD was described in a patent by David E. Olson and colleagues at Delix Therapeutics in 2021. Its pharmacology was not described.

LSD (left) and 10,11-seco-LSD (right) chemical structures.

Partial lysergamide
Seco-LSD
Secoergoline
NDTDI (8,10-seco-LSD)
DEIMDHPCA (3,5-seco-LSD)

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